abstract：BACKGROUND:End-stage renal disease and the need for chronic hemodialysis is an indication for hepatitis B vaccination, but up to half of dialysis patients fail to respond to a 40 microg/dose i.m. three-dose primary series of recombinant hepatitis B vaccine. Only another 10-20% respond to additional boosting doses of va...

journal_title：Clinical nephrology

authors： Evans TG,Schiff M,Graves B,Agosti J,Barritt ML,Garner D,Holley JL

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:It has been proposed that, once renal function has been restricted in chronic kidney disease, compensatory hyperfiltration results in a compulsory deterioration of renal function. PATIENTS AND METHODS:In this study, 83 patients originally starting from a serum creatinine (S(crea)) between 2.0 and 5.0 mg/dl ...

journal_title：Clinical nephrology

authors： Rottey S,Vanholder R,De Schoenmakere G,Lameire N

更新日期：2000-07-01 00:00:00

abstract：:Sulfadiazine acute nephrotoxicity is reviving specially because of its use in toxoplasmosis in HIV-positive patients. We report 4 cases, one of them in a previously healthy person. Under treatment with sulfadiazine they developed oliguria, abdominal pain, renal failure and showed multiple radiolucent renal calculi in ...

journal_title：Clinical nephrology

authors： Crespo M,Quereda C,Pascual J,Rivera M,Clemente L,Cano T

更新日期：2000-07-01 00:00:00

abstract：:AL (amyloid light-chain) amyloidosis is a plasma cell disorder in which depositions of amyloid light-chain protein cause progressive organ failure. Virtually all patients with AL amyloidosis have a monoclonal protein in the serum or urine or a monoclonal population of plasma cells in the bone marrow. The most common t...

journal_title：Clinical nephrology

authors： Sezer O,Eucker J,Jakob C,Possinger K

更新日期：2000-06-01 00:00:00

abstract：AIM:A major cause of morbidity for hemodialysis patients is vascular access failure and/or occlusion. It is commonly believed that an increased frequency of dialysis sessions, among other factors, might lead to a higher rate of fistula complications. MATERIALS AND METHODS:To evaluate if patients on daily hemodialysis ...

journal_title：Clinical nephrology

authors： Quintaliani G,Buoncristiani U,Fagugli R,Kuluiranu H,Ciao G,Rondini L,Lowenthal DT,Reboldi G

更新日期：2000-05-01 00:00:00

abstract：AIM AND METHODS:Epitope analysis of sera from 20 patients with myeloperoxidase anti-neutrophil cytoplasmic antibody- (MPO-ANCA) associated glomerulonephritis was examined by Western blotting using a panel set of recombinant deletion mutants of MPO. Sera from 19 patients reacted with recombinants of MPO heavy chain, whe...

journal_title：Clinical nephrology

authors： Fujii A,Tomizawa K,Arimura Y,Nagasawa T,Ohashi YY,Hiyama T,Mizuno S,Suzuki K

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:We encountered two cases of Chinese herb-induced Fanconi syndrome in Japan. One component of the chinese medicine was "Kan-mokutsu" (Aristolochia manshuriensis) in which aristolochic acids (AAs) were detected. METHODS:Renal biopsy showed flattening of proximal tubular epithelial cells and paucicellular inte...

journal_title：Clinical nephrology

authors： Tanaka A,Nishida R,Maeda K,Sugawara A,Kuwahara T

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:Decreases in bone mass and increased susceptibility to fractures are well-recognized complications in organ transplants. SUBJECTS AND METHODS:We performed a cross-sectional study on 60 patients (40 males, 20 females, mean age 43.2 +/- 1.06, SE range 22 - 70) who underwent kidney transplantation (KTX) 55.6 +...

journal_title：Clinical nephrology

authors： D'Angelo A,Calò L,Giannini S,Carraro G,Bonfante L,Favaro S,Zaninotto M,Perin N,Di Landro D,Rigotti P,Antonello A

更新日期：2000-04-01 00:00:00

abstract：:We report two cases with congenital portosystemic shunt who developed renal lesions without liver cirrhosis. Clinically, both cases showed proteinuria and mild hematuria at 9 and 6 years of age, respectively. In one case, the renal lesion was associated with normal renal function, but nephrotic syndrome followed by ch...

journal_title：Clinical nephrology

authors： Karashima S,Hattori S,Nakazato H,Awata H,Seguchi S,Ikeda S,Sera Y,Endo F

更新日期：2000-03-01 00:00:00

abstract：:The erythrocyte is a highly specialized cell whose main functions are oxygen transport and the mediation of carbon dioxide transport. Energy production in the mature erythrocyte depends on glycolysis, with glucose as the principal substrate. Glycolysis and the oxidative pentose phosphate pathway generate NADH and NADP...

journal_title：Clinical nephrology

authors： Siems WG,Sommerburg O,Grune T

更新日期：2000-02-01 00:00:00

abstract：:Patients with diabetes and/or severe arteriosclerosis are often unable to tolerate volume removal during hemodialysis (HD) and develop hemodialysis-induced symptoms. These problems can be omitted by well-balanced correction of the acid/base status. We compared 20 high-risk patients which were either treated with stand...

journal_title：Clinical nephrology

authors： Hampl H,Berweck S,Ludat K,Fischer HC,Hertel J

更新日期：2000-02-01 00:00:00

abstract：AIM:To facilitate the understanding of the transporter function of human renal tubular cells, we have developed a simple method using primary cultured proximal tubule (PT) cells isolated from voided urine. METHODS:PT cells grown to confluence on glass coverslips could be identified by parallel arrays of spindle cells ...

journal_title：Clinical nephrology

authors： Inoue CN,Kondo Y,Ohnuma S,Morimoto T,Nishio T,Iinuma K

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:The excess of cardiovascular disease in end-stage renal disease (ESRD) patients is unexplained, but could relate to altered intrinsic vascular wall properties, such as increased arterial stiffness, which could be mediated by hyperhomocysteinemia. We investigated potential determinants of carotid artery stiff...

journal_title：Clinical nephrology

authors： van Guldener C,Lambert J,ter Wee PM,Donker AJ,Stehouwer CD

更新日期：2000-01-01 00:00:00

abstract：AIM:Renovascular hypertension (RVH) is associated with a high prevalence of target organ damage and a high mortality. We have undertaken this follow-up study to assess the role played by comorbid conditions, and pharmacological treatment on survival, and on renal function in 64 patients with diffuse atherosclerotic vas...

journal_title：Clinical nephrology

authors： Losito A,Gaburri M,Errico R,Parente B,Cao PG

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:We previously demonstrated that the supernatants of cultured concanavalin-A (con-A) stimulated peripheral blood mononuclear cells (PBMC) from patients with minimal change nephrotic syndrome (MCNS) increased the urinary protein excretion in injected rats and suggested that PBMC released a factor, which we cal...

journal_title：Clinical nephrology

authors： Kondo S,Yoshizawa N,Kusumi Y,Takeuchi A,Torikata C

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Hemodiafiltration is used to increase the convective transport and thereby the elimination of small and middle molecules, mainly beta2-microglobulin (beta2-M) across the dialysis membranes. There is little information concerning urea, creatinine, beta2-M and principally phosphate kinetics during hemodiafiltr...

journal_title：Clinical nephrology

authors： Zehnder C,Gutzwiller JP,Renggli K

更新日期：1999-09-01 00:00:00

abstract：:This study reviews the pattern of glomerulonephritis (GN) in Singapore over the past 2 decades. In the earlier decade the pattern was typical of most Asian countries with mesangial proliferative GN (Mes GN) (56%) as the most common form of primary GN including the nephrotic syndrome (40%). In the 2nd decade the patter...

journal_title：Clinical nephrology

authors： Woo KT,Chiang GS,Pall A,Tan PH,Lau YK,Chin YM

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:The vascular permeability factor (VPF) is a lymphokine that has been shown to play a role in minimal-change nephrotic syndrome (MCNS). A better understanding of the mechanisms that upregulate VPF release is of basic importance to control the immune system in nephrotic syndrome (NS). Interleukin (IL)-15 is a ...

journal_title：Clinical nephrology

authors： Matsumoto K,Kanmatsuse K

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Inappropriate correction of chronic hyponatremia could lead to major neuropathological sequelae. In man, the risk of brain myelinolysis increases strikingly when correction of the serum sodium exceeds 10-15 mEq/l/24 h. No treatment is actually available for this iatrogenic brain injury. However, recent exper...

journal_title：Clinical nephrology

authors： Soupart A,Ngassa M,Decaux G

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Leptin, the product of the obese gene, is produced exclusively in fat cells. SUBJECTS, MATERIALS AND METHODS:To evaluate the clinical significance of measuring serum leptin in 56 patients with chronic renal failure on hemodialysis (HD), we measured leptin levels using radioimmunoassay in 34 normal volunteer...

journal_title：Clinical nephrology

authors： Nishikawa M,Takagi T,Yoshikawa N,Shouzu A,Murakami T,Kono M,Owae H,Tanaka K,Iwasaka T,Inada M

更新日期：1999-05-01 00:00:00

abstract：:Sulpyrine is commonly used in Japan. We report a case of acute renal failure due to acute tubulointerstitial nephritis (ATIN), which we believe was associated with the use of sulpyrine. ...

journal_title：Clinical nephrology

authors： Kitazawa K,Sugisaki T

更新日期：1999-04-01 00:00:00

abstract：:Glomerulocystic disease is an uncommon cystic renal condition characterized by cystic dilatation forming a glomerular cyst. The pathogenesis of this familial disease is unknown. We performed a serial section study using a biopsy specimen of a 16-year old female patient with glomerular cystic disease who had a family h...

journal_title：Clinical nephrology

authors： Hotta O,Sato M,Furuta T,Taguma Y

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Nonsteroidal anti-inflammatory drugs (NSAID) e.g. aspirin, indomethacin are reported in epidemiological and experimental studies to reduce the risk for colo-rectal cancer and potentially other malignant tumors. METHODS:We examined the effect of NSAIDs on tumor prevalence in abusers of mixed analgesics conta...

journal_title：Clinical nephrology

authors： Bucher C,Jordan P,Nickeleit V,Torhorst J,Mihatsch MJ

更新日期：1999-02-01 00:00:00

abstract：:Anemia is a common complication of chronic renal failure (CRF). With the availability of recombinant human erythropoietin (rhEPO) over the last decade, much progress has been made in the management of anemia in patients with end-stage renal disease (ESRD) [Eschbach 1995, Gimenez and Scheel 1994, Muirhead et al. 1995, ...

journal_title：Clinical nephrology

authors： Drüeke TB,Eckardt KU,Frei U,Jacobs C,Kokot F,McMahon LP,Schaefer RM

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:End-stage renal disease (ESRD) patients infected with human immunodeficiency virus (HIV) have poor survival on maintenance hemodialysis. Only a few studies have evaluated survival time on the basis of demographic and clinical factors. The clinical category of the HIV infection and total CD4 counts are commonl...

journal_title：Clinical nephrology

authors： Dave MB,Shabih K,Blum S

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Since dietary protein is required for replenishment of lean body mass and since dialysis patients may have a significant increase in body fat, it makes sense to express protein intake normalized per lean body mass. However, this may be complicated since the daily protein requirements of man, based on studies...

journal_title：Clinical nephrology

authors： Leibowitz J,Uribarri J

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Tumoral calcinosis, an inherited metabolic disorder, has been described with increasing frequency over the last 20 years [Drueke 1966]. It is characterized by massive calcium phosphate deposits in periarticular tissues, usually around large joints, especially the hips, knees and elbows (editorial in Lancet 1...

journal_title：Clinical nephrology

authors： Apostolou T,Tziamalis M,Christodoulidou C,Fountas P,Billis A

更新日期：1998-10-01 00:00:00

abstract：:The urinary excretion of N-acetyl-beta-glucosaminidase (NAG), a lysosomal enzyme of the renal tubular cells was analyzed in 177 women divided into nonpregnant healthy controls (n = 46), normal pregnant women in their third trimester (n = 49), pregnant women with transient hypertension (n = 43), and women with preeclam...

journal_title：Clinical nephrology

authors： Pérez-Blanco FJ,Sanabria MC,Huertas JM,Cantero J,Rodríguez-Cuartero A

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVE:To study bone density in hypercalciuric patients, when classified according to the main metabolic defect. METHODS:We studied 49 patients, aged 19-60 years with calcium stones and idiopathic hypercalcuria. All subjects underwent an evaluation of mineral metabolism and a spinal and femoral DEXA measurement. Th...

journal_title：Clinical nephrology

authors： Giannini S,Nobile M,Sartori L,Calò L,Tasca A,Dalle Carbonare L,Ciuffreda M,D'Angelo A,Pagano F,Crepaldi G

更新日期：1998-08-01 00:00:00

abstract：:We investigated the therapeutic effect of low density lipoprotein adsorption (LDL-A) in 14 patients who had focal glomerulosclerosis (FGS) with the nephrotic syndrome resistant to steroids. Patients received a total of 6 sessions (2 times a week for 3 weeks). The levels of total cholesterol, triglycerides and low-dens...

journal_title：Clinical nephrology

authors： Yokoyama K,Sakai S,Sigematsu T,Takemoto F,Hara S,Yamada A,Kawaguchi Y,Hosoya T

更新日期：1998-07-01 00:00:00

abstract：AIM:Renal functional reserve (RFR), resulting from an increase in glomerular filtration (GFR) after protein load, is a matter of debate. In kidney transplant recipients most studies have failed to show conclusive results, reporting either the absence, the reduction or the presence of renal reserve in normo-functioning ...

journal_title：Clinical nephrology

authors： Fagugli RM,Buoncristiani U,Selvi A,Cozzari M,Fedeli L,Bini V,Papi F,Falorni A,Palumbo R

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:There is an inverse relationship between changes in the concentration of sodium in plasma (PNa) and intracellular fluid (ICF) volume. Intakes and losses of sodium (Na), potassium (K) and water can be divided into two volumes: isotonic and electrolyte-free water (EFW). Calculations of these volumes assess a t...

journal_title：Clinical nephrology

authors： Mallié JP,Ait-Djaffer Z,Laroche F,Mario J,Perrier JC,Voltz C,Halperin ML

更新日期：1998-05-01 00:00:00

abstract：:A 52-year-old man was admitted to hospital because of declining renal function. Some months previously, biopsy from a mediastinal lymph node had shown Castleman's disease (angiofollicular lymph node hyperplasia). By now, a renal biopsy showed massive interstitial infiltration of predominantly plasma cells without sign...

journal_title：Clinical nephrology

authors： Frøkjaer Thomsen O,Ladefoged J

更新日期：1998-05-01 00:00:00

abstract：:D-amino acid oxidase (DAO) is an enzyme released from the kidney, and a method for its enzymatic assay was developed by our group for urine specimens. A clinical evaluation of the test was performed for healthy individuals and patients with various types of nephropathy. 1) The normal reference interval was 0-10.0 micr...

journal_title：Clinical nephrology

authors： Kawasaka K,Tatsumi N

更新日期：1998-04-01 00:00:00

abstract：:The 5-aminosalicylic acid (5-ASA) is currently the treatment of choice for patients with inflammatory bowel disease. It can be administered as sulfasalazine (5-ASA + sulfapyridine), mesalazine (5-ASA + resins or gels) and olsalazine (two molecules of 5-ASA). The recent trend has been to use formulations without sulfap...

journal_title：Clinical nephrology

authors： Calviño J,Romero R,Pintos E,Losada E,Novoa D,Güimil D,Mardaras J,Sanchez-Guisande D

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:Both four-site skinfold anthropometry (FSA) and bioelectrical impedance analysis (BIA) claim to be useful in routine clinical practice of maintenance dialysis as easy methods to assess nutritional status. The purpose of this study was to investigate which of these two methods is to be preferred. METHODS:Bot...

journal_title：Clinical nephrology

authors： Oe B,de Fijter CW,Oe PL,Stevens P,de Vries PM

更新日期：1998-03-01 00:00:00

abstract：:Patients with chronic renal failure (CRF) often have autonomic cardiac dysfunction, which can be assessed by measuring heart rate variability (HRV). This dysfunction prediposes the patients to sudden cardiac death. This study describes 24-hour HRV in patients with CRF compared to HRV in patients with a previous myocar...

journal_title：Clinical nephrology

authors： Christensen JH,Aarøe J,Knudsen N,Dideriksen K,Kornerup HJ,Dyerberg J,Schmidt EB

更新日期：1998-02-01 00:00:00

abstract：:Antineutrophil cytoplasmic antibodies positivity with cytoplasmic pattern (C-ANCA) and proteinase-3 (PR-3) specificity was found in two patients with both subacute bacterial endocarditis (SBE) and glomerular involvement. Renal biopsy showed membranoproliferative glomerulonephritis in one case and focal segmental glome...

journal_title：Clinical nephrology

authors： Subra JF,Michelet C,Laporte J,Carrere F,Reboul P,Cartier F,Saint-André JP,Chevailler A

更新日期：1998-01-01 00:00:00

abstract：:The association of xanthogranulomatous pyelonephritis (XPN) and systemic amyloidosis is extremely rare. This association has been described in only six cases. We present a 4-year-old male admitted with a history of anuria and abdominal pain. Investigations revealed multiple calculi in both kidneys. A right pyelolithot...

journal_title：Clinical nephrology

authors： Işlek I,Bariş S,Albayrak D,Büyükalpelli R,Sancak R

更新日期：1998-01-01 00:00:00

abstract：:Hypertension is frequently observed in end-stage renal failure. We analysed the incidence and severity of hypertension as well as antihypertensive treatment in a large group of patients on renal replacement therapy (RRT). Questionnaires were sent to all 49 dialysis centers caring for a total of 2090 patients on RRT in...

journal_title：Clinical nephrology

authors： Zazgornik J,Biesenbach G,Forstenlehner M,Stummvoll K

更新日期：1997-12-01 00:00:00